ABSTRACT
Coronavirus, at present, has created major health havoc across the world. It has been declared as a global health threat by the World Health Organization (WHO). The world has already experienced major outbreaks of coronaviruses previously. A few of the major outbreaks from the past include Severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002, Middle East Respiratory Syndrome (MERS-CoV) in 2012, and the present Severe acute respiratory syndrome coronavirus 2(SARS-CoV-20). All of these belonged to Coronaviridae and have been known to cause respiratory infections mostly. The infection ranges from mild to severe and even death with common symptoms of fever, chills, shortness of breath, gastrointestinal problems, etc. This respective review article discusses the prominent members of Coronaviridae in detail. It highlights the major outbreaks of coronaviruses faced by the world and the substantial mortalities caused by them. It also talks about the most effectively used methods of diagnosis for such viruses andenumerates the antivirals and drug combinations found effective against the past and present coronavirus infections. Coronavirus is at present the hottest topic for study due to COVID-19. This review article aims to collectively present all the relevant data for our readers which can help them to strengthen their basic knowledge for future studies.